DefenAge Clinical Power Trio + | LovelySkin
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DefenAge Clinical Power Trio + Original - Limited Edition

DefenAge Clinical Power Trio +

3-Piece Set
$318.00 ($380 Value)

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Highlights
  • Fades signs of aging with peptides
  • Addresses fine lines and wrinkles
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Product Overview

DefenAge Clinical Power Trio + provides restorative skin care with a MEGA-Sized BioSerum.

This set includes three powerful pieces of an anti-aging regimen. The multitasking formulas make use of defensins. Exclusive to DefenAge, this ingredient tells our body to activate our dormant reserves of young cells, helping restore more youthful-looking skin.

This limited-edition set includes a larger size of the 8-in-1 BioSerum, with 50% more serum than the original.

Set Includes:

  • 8-in-1 BioSerum (1.5 fl oz): This bestselling and award-winning formula packs the power of eight serums into one, visibly smoothing wrinkles, shrinking pores, brightening discoloration, calming redness and more.
  • 24/7 Barrier Balance Cream (1.5 fl oz): With restorative ingredients like niacinamide and hyaluronic acid, this cream replenishes the moisture barrier and promotes visibly smoother and more even-toned skin.
  • 2-Minute Reveal Masque (2.5 oz): Using enzymes and ultrafine sugar crystals, this award-winning face mask brightens, reduces the look of pores and softens rough skin.

Experience an award-winning regimen with DefenAge Clinical Power Trio +.

Note: Masque not recommended for acne, rosacea, extremely sensitive or abraded skin.

Highlights

  • Fades signs of aging with peptides
  • Addresses fine lines and wrinkles
  • Includes a MEGA-sized BioSerum

Ingredients

Featured Ingredient

Niacinamide

A water-soluble form of vitamin B3 that reduces the appearance of wrinkles.

Original:

Barrier Balance Cream: Water (Aqua) Carthamus Tinctorius (Safflower) OleosomesButyrospermum Parkii (Shea) Butter Macadamia Integrifolia Seed Oil Niacinamide Yeast Extract Ammonium Acryloyldimethyltaurate/ VP CopolymerHelianthus Annuus (Sunflower) Seed Oil Phospholipids Alpha-Defensin 5 Beta-Defensin 3 Hyaluronic Acid Ophiopogon Japonicus Root ExtractHydrolyzed Candida Saitoana ExtractSea Whip Extract Lycium Chinense Fruit Extract Vaccinium Angustifolium Fruit ExtractVaccinium Marcrocarpon Fruit (Cranberry) Fruit ExtractRosmarinus Officinalis (Rosemary) Leaf Extract Panthenol Albumin Tocopheryl Acetate Ubiquinone L-Alanyl-L-GlutamineLeuconostoc/Radish Root Ferment Filtrate SH Oligopeptide-1Xanthan Gum Phytic Acid Polysorbate 20 Caprylic/Capric Triglyceride Phenoxyethanol Caprylyl Glycol Ethylhexylglycerin Hexylene Glycol Potassium Sorbate Sodium Chloride Fragrance

8-in-1 BioSerum: Water (Aqua) Cyclopentasiloxane Glycerin Niacinamide Sinorhizobium Meliloti Ferment FiltrateDimethicone Polysorbate 20 Dimethicone/Vinyl Dimethicone Crosspolymer Lauryl PEG-9 Polydimethylsiloxyethyl DimethiconeAmmonium Acryloyldimethyltaurate/ VP CopolymerPhospholipids Alpha-Defensin 5 Beta-Defensin 3 Palmitoyl Tripeptide-38 Sodium Hyaluronate Arabidopsis Thaliana ExtractSea Whip Extract Ergothioneine Helianthus Annuus (Sunflower) Seed Oil Rosmarinus Offinalis (Rosemary) Leaf ExtractSH Oligopeptide-1Tocopheryl Acetate Ubiquinone Leuconostoc/Radish Root Ferment Filtrate Albumin L-Alanyl-L-GlutamineCaprylic/Capric Triglyceride Cetyl Hydroxyethylcellulose Lecithin Hydroxypropyl Cyclodextrin Phytic Acid Phenoxyethanol Caprylyl Glycol Ethylhexylglycerin Hexylene Glycol Sodium Chloride

2-Minute Reveal Masque: Butylene Glycol PEG-8 Tapioca StarchSucroseTitanium Dioxide Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Squalane Polysorbate 60 Carica Papaya (Papaya) FruitPapain Aloe Barbadensis Leaf Juice Lactobacillus/Pumpkin Ferment ExtractLactobacillus/Punica Granatum Fruit Ferment ExtractSea Whip Extract Cananga Odorata Flower OilCitrus Aurantium Dulcis (Orange) Peel Oil Caprylic/Capric Triglyceride Lactic Acid Phenoxyethanol Caprylyl Glycol Ethylhexylglycerin Hexylene Glycol

Fragrance-Free:

2 Minutes Reveal Masque: Butylene Glycol PEG-8 Tapioca StarchSucroseTitanium Dioxide Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Squalane Polysorbate 60 Carica Papaya (Papaya) FruitPapain Aloe Barbadensis Leaf Juice Lactobacillus/Pumpkin Ferment ExtractLactobacillus/Punica Granatum Fruit Ferment ExtractSea Whip Extract Cananga Odorata Flower OilCitrus Aurantium Dulcis (Orange) Peel Oil Caprylic/Capric Triglyceride Lactic Acid Phenoxyethanol Caprylyl Glycol Ethylhexylglycerin Hexylene Glycol

24/7 Barrier Balance Cream: Water (Aqua) Carthamus Tinctorius (Safflower) OleosomesButyrospermum Parkii (Shea) Butter Macadamia Integrifolia Seed Oil Niacinamide Yeast Extract Ammonium Acryloyldimethyltaurate/ VP CopolymerHelianthus Annuus (Sunflower) Seed Oil Phospholipids Alpha-Defensin 5 Beta-Defensin 3 Hyaluronic Acid Ophiopogon Japonicus Root ExtractHydrolyzed Candida Saitoana ExtractSea Whip Extract Lycium Chinense Fruit Extract Vaccinium Angustifolium Fruit ExtractVaccinium Marcrocarpon Fruit (Cranberry) Fruit ExtractRosmarinus Officinalis (Rosemary) Leaf Extract Panthenol Albumin Tocopheryl Acetate Ubiquinone L-Alanyl-L-GlutamineLeuconostoc/Radish Root Ferment Filtrate SH Oligopeptide-1Xanthan Gum Phytic Acid Polysorbate 20 Caprylic/Capric Triglyceride Phenoxyethanol Caprylyl Glycol Ethylhexylglycerin Hexylene Glycol Potassium Sorbate Sodium Chloride

8-in-1 Bio Serum: Water (Aqua) Cyclopentasiloxane Glycerin Niacinamide Sinorhizobium Meliloti Ferment FiltrateDimethicone Polysorbate 20 Dimethicone/Vinyl Dimethicone Crosspolymer Lauryl PEG-9 Polydimethylsiloxyethyl DimethiconeAmmonium Acryloyldimethyltaurate/VP Copolymer Phospholipids Alpha-Defensin 5 Beta-Defensin 3 Palmitoyl Tripeptide-38 Sodium Hyaluronate Arabidopsis Thaliana ExtractSea Whip Extract Ergothioneine Helianthus Annuus (Sunflower) Seed Oil Rosmarinus Offinalis (Rosemary) Leaf ExtractSH Oligopeptide-1Tocopheryl Acetate Ubiquinone Leuconostoc/Radish Root Ferment Filtrate Albumin L-Alanyl-L-GlutamineCaprylic/Capric Triglyceride Cetyl Hydroxyethylcellulose Lecithin Hydroxypropyl Cyclodextrin Phytic Acid Phenoxyethanol Caprylyl Glycol Ethylhexylglycerin Hexylene Glycol Sodium Chloride

Directions

Shipping & Returns

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Return Policy: This product is non-returnable

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Special Shipping Requirements: ORM-D Class
ORM-D classified products such as aerosol sprays, nail polish, perfume and products with high alcohol content may only be shipped using a ground method within the Continental US.

Availability: Depends on selected option.

Questions & Answers

Submit your question about this product to our talented team of Customer Care Representatives, and we'll get back to you as soon as possible!


Product Specifications

Item Id S37322
Item Id S37323
Item Id
Size 3-Piece Set
Benefits
  • Fades signs of aging with peptides
  • Addresses fine lines and wrinkles
  • Includes a MEGA-sized BioSerum
Skin Type
  • Combination
  • Dry
  • Mature
  • Normal
  • Oily
Product Type
  • Skin Care Sets
  • Face Serums
  • Face Masks
  • Face Creams
Key Ingredient
  • Hyaluronic Acid
  • Niacinamide
  • Peptides
  • Sugar
  • Vitamin E
Product Form
  • Cream
  • Serum
Preferences
  • Cruelty Free
  • Fragrance Free
  • Gluten Free
  • Paraben Free
  • Sulfate Free
  • Vegan
Application Area
  • Face
Concern
  • Anti-Aging
  • Dark Spots
  • Dark Circles
  • Large Pores
  • Rosacea
  • Congested Skin
  • Puffiness
  • Redness
  • Sun Damage
Features
  • Exfoliating

About the Brand

Customer Reviews (19)

Overall Rating

4.9
Based on 19 reviews

Review Summary

5 Stars
18 reviews
4 Stars
1 review

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LovelySkin Customer

Verified Purchase

March 06, 2025

Love!

I love these products! I have been using them for about a year and a half now and I notice a big difference in my skins texture as well as pore size.

0 people found this helpful

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Loly

Verified Purchase

September 11, 2024

worth every penny

I've been using Defenage for years - the mask/scrub is phenomenal! Every now and then I will try other products, however I have not found anything that compares.

0 people found this helpful

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Luvtrails

Verified Purchase

June 14, 2024

Wonderful products!

I have used this trio for many years and will continue. My dermatologist recommended DefenAge. It never goes on sale, but it’s worth the price, imho!

0 people found this helpful

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Majohns

Verified Purchase

June 06, 2024

Superior product

I have been using this product for over 5 years and still love it.

0 people found this helpful

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LovelySkin Customer

Verified Purchase

November 03, 2023

Works well

This is the second set I’ve purchased. Absorbs well, makes my skin feel great. The mask really does the trick. Highly recommend. Expensive, but lasts a long time.

0 people found this helpful

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LovelySkin Customer

Verified Purchase

October 26, 2023

Excellent Product

I've been using this trio for several years and my skin is smooth, hydrated and glowing. My dermatologist recommends it and says there is none better on the market and I agree! Worth every penny!

0 people found this helpful

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QowoqiqiqiBbb

Verified Purchase

March 25, 2023

My go to product

This is one of the first and only items I ever used that I noticed an immediate improvement in my skin. I do have to say that the wow factor seemed to wear off over time but it’s still a great product I would highly recommend!

0 people found this helpful

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LovelySkin Customer

Verified Purchase

May 09, 2022

DefenAge

I have been using DefenAge for the past two weeks and I am starting to see a difference. I can’t wait to see more improvement in a few more weeks. Skin feels and looks much better!

0 people found this helpful

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APolotnik

Verified Purchase

February 26, 2022

My skin is glowing!

I’ve been using this set for over a year and my skin is the best it’s ever been! I always get compliments on my skin! I changed one time to another brand and will never do that again. I am a lifetime customer of DefenAge and Lovelyskin!

0 people found this helpful

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LovelySkin Customer

Verified Purchase

February 14, 2022

Spectacular!!!

I finally found something that actually works! I will admit it’s pricey but it’s amazing! I have weird texture on my skin and a lot of redness and it’s all gone. It also lessens wrinkles. I love this stuff it’s my favorite product!

0 people found this helpful

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WandaSue

Verified Purchase

January 13, 2022

Defenage - perfect name for product

Best product line - a bit pricey but worth it for the results

0 people found this helpful

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DawnB50

Verified Purchase

January 08, 2022

The Best Skincare Routine

The wash, moisturizer, serum & 2 minute miracle are amazing! I've been using for 2 years now & my skin has never looked better!

0 people found this helpful

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Esmee007

Verified Purchase

December 04, 2021

DefenAge Power Trio+

Love these products! I love the simplicity of this line. It has completely normalized my skin. I was experiencing oiliness, dryness, acne and sensitivity like I had never dealt with before. I decided to incorporate this line with my normal face wash and it fixed all of my issues. I then incorporated the mask and it took everything to the next level. My skin feels amazing and smooth and looks great. My fine lines and acne scars are less noticeable. I have used many professional product lines and had many professional treatments and nothing has worked as well or as quickly for me. I highly recommend this line but would suggest starting with the 24 hour kits first to make sure it will work for you.

0 people found this helpful

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Mal

Verified Purchase

November 19, 2021

DefenAge

Good stuff

0 people found this helpful

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Bluzegirl

Verified Purchase

September 16, 2021

Very simple routine

I am loving the simplicity of these products. My skin feels smooth and fresh. It has only been a few weeks and I like how my skin is responding. I like that they offer the unscented version, which is the one I use.

0 people found this helpful

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EyeJen

Verified Purchase

September 03, 2021

Great product

My skin is smoother and brighter. I have been using it for 6 weeks a day been very satisfied.

0 people found this helpful

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Mam3

Verified Purchase

August 27, 2021

Defenage Power Trio

I have used many products and Defenage is the best! My skin responds beautifully to these products. The 8 in 1 bio serum is phenomenal!

0 people found this helpful

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CP3

Verified Purchase

July 30, 2021

Recommended by my dermatologist

My dermatologist recommended this for my skin. I’m 67 years old but don’t have a lot of wrinkles. My skin tends to be on the dry side. My dermatologist said she uses it as well. I’m guessing she’s in her 40’s. I bought a previous kit but the bottle of serum was smaller. This kit has the same full size as the cream. I like this product a lot. The cream and serum are not heavy nor sticky.

0 people found this helpful

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LovelySkin Customer

Verified Purchase

June 29, 2021

Repaired my skin

Used after skin pen micro needling - transformed my dry, peeling skin to smooth and growing. A forever repurchase for me!

0 people found this helpful

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