Dermatologist owned & operated. Visit Schlessinger MD
Free 2-3 day delivery most orders, no minimums
LovelySkin
Today's Special Offer: 30% Off Pre-Black Friday Sale + 33% Off Doorbusters + Free $50 Gift Shop Now
View more from MEG 21

MEG 21 Age-Defying Hand Treatment

3.4 oz
This product is no longer available

We recommend the following product instead:

Highlights

  • Stimulates skin renewal
  • Deeply hydrates skin
  • Protects skin from damage

You'll Love These Too!

Product Overview

Keep hands soft and smooth with this cream.

A team of scientists conducting diabetes research at the Fox Chase Research Center in Philadelphia, PA discovered the presence of a toxic substance , 3-deoxyglucosone (3DG), in skin. These scientists then uncovered the link between 3DG, skin aging, collagen depletion, and loss of skin elasticity. Further scientific research led the team to develop Supplamine, a powerful new formulation for addressing the effects of glycation and oxidative stress on skin. Clinical tests demonstrate that Supplamine inhibits the harmful effects of 3DG, reduces the appearance of fine lines and wrinkles, increases moisture and skin glow, and improves overall skin texture, firmness and smoothness. Noticeable results occur in just four weeks or less! MEG 21 Age Defying Hand Treatment is far beyond a good moisturizer. This unique formulation powered by Supplamine revitalizes hands and reduces the appearance of aging by counteracting the effects of glycation and oxidative stress on skin. Supplamine contains an intensive combination of amino acids, anti-inflammatory agents, and anti-oxidants that target fine lines, wrinkles, dryness and uneven skin tones.

Key Ingredients

  • Supplamine: Patented ingredient to intercept and reverse glycation, inflammation and metabolic oxidation caused by 3DG sugars in the skin
  • Cocoa Seed Butter – emollient rich source of antioxidants
  • Jojoba Oil – Emolliency similar to natural oil structure produced by the skin
  • Evening Primrose Oil – Clears pathway to allow barrier penetration; natural skin softener and conditioner
  • Vitamin E – Healing Antioxidant
  • Aloe Leaf Extract – Natural anti-irritant to reduce inflammation
  • Lemon Peel Extract – skin conditioner and tyrosinase inhibitor
  • Shea Butter – natural antioxidant rich emollient

 

Highlights

  • Reduces signs of aging
  • Relieves dryness and irritation
  • Hydrates and protects hands

Ingredients

Directions

Shipping & Returns

Free U.S. Shipping. Period. View Our Shipping Policy

Return Policy: This product is non-returnable

Return Policy: View Our Return Policy

Special Shipping Requirements: ORM-D Class
ORM-D classified products such as aerosol sprays, nail polish, perfume and products with high alcohol content may only be shipped using a ground method within the Continental US.

Availability: This product is no longer available.

Product Specifications

Customer Reviews (42)

Read all reviews
Profile picture of lss.

lss

Verified Purchase

August 24, 2023

Not my favorite

Not wowed by this hand cream. I have a feeling no matter what anyone says, all hand creams are probably pretty much the same.

Profile picture of bear.

bear

Verified Purchase

June 17, 2023

Found my new hand cream!

Love this and it has no fragrance, and it seems to be a great anti-aging product so far!

Default profile picture.

LovelySkin Customer

Verified Purchase

May 04, 2023

Now My Go-To Hand Treatment!

Confession: I was skeptical about this product, but the reviews convinced me to try it, and I'm so glad I did! This MEG 21 treatment works wonders for skin suppleness and wrinkling. My hands look and feel younger, smoother, more emoliated, and far better hydrated. I'm a great Before - I have 65-year-old hands that spent a lot of time in the high desert, along with Raynaud's Syndrome - which reduces circulation quality on the hands - so my hands were showing their years. But not any more! I now pair this MEG 21 with a hand cream from a different brand from the fine folks here at LovelySkin and apply liberally. Don't like to get caught without it! MEG 21 is a total game-changer.

Default profile picture.

LovelySkin Customer

Verified Purchase

November 06, 2022

Meg21 Hand Treatment

Excellent hand treatment -- I use Meg21 on my face as well. I use it twice a day, just on the top of my hands.

Default profile picture.

LovelySkin Customer

Verified Purchase

July 06, 2022

Great Hand & Arm Product

I was looking for a product for my hands and arms. This product is great and I have activated a auto replenishment on it so I can be sure to have it on hand. The texture of my skin improved very quickly and some hand bruising I was getting has subsided since using this product.

Profile picture of susanb26.

susanb26

Verified Purchase

June 27, 2022

Best I’ve Found, But…

…that’s not saying much. Perhaps my 65-year-old hands are beyond help. I have been using this almost every night before bed for almost 6 months. I like the way my hands look when I put it on, but it’s not super-moisturizing and there seem to be no cumulative effects. I just keep buying it coz I haven’t yet found anything better.

Profile picture of Mella.

Mella

Verified Purchase

February 24, 2022

Okay

This is fairly moisturizing. Haven’t noticed a huge difference in my hands, however. Maybe after a bit more time it will get better.

Profile picture of blc59.

blc59

Verified Purchase

January 25, 2022

It makes my hands look nicer

I have only been using for a few weeks but it appears that the back of my hands look and feel smother as well are a little less spotted. I am looking forward to seeing how they look after a few months of use.

Profile picture of Debann.

Debann

Verified Purchase

January 09, 2022

Great Handcream

I think I need to use it a little longer for the best results but so far I am loving how it makes my hands look and feel. I would recommend it to anyone looking to improve the appearance of their hands!

Profile picture of Anonmously.

Anonmously

Verified Purchase

December 23, 2021

Meg 21

1st time user and after 3 weeks, I have a softer feel than any other lotion has provided - can't wait to see the difference at 6 months:)

Default profile picture.

LovelySkin Customer

Verified Purchase

August 06, 2021

Smooth and Soft Hands

I purchased to soothe my very dry aging hands and this hand treatment delivers results. I apply twice a day, in the am after I'm done applying my skincare and evening before bed. The Meg21 treatment absorbs fast and leaves no greasy film. To soon to see results of faded dark pigments but after use, the tops of my palms look firmer. I also use on rough dry elbows.

Default profile picture.

LovelySkin Customer

Verified Purchase

August 01, 2021

Really Works!

This lotion takes patience but after using it every night for a month, I definitely see improvement in the look and feel of the skin on my hands. Reasonably priced. Recommend.

Profile picture of Radu.

Radu

Verified Purchase

May 06, 2021

Amazing & Effective

I'm 43 with fair skin. I take great care of my face but have neglected my hands. The last few years I've noticed my hands aging. I've been using this lotion for the tops of my hands only for about a week. I am seriously impressed with the difference! Crepy skin is slightly reduced but there is a significant decrease in hyperpigmentation/age spots. I will never be without this product again! And I'm going to purchase driving gloves too!

Default profile picture.

LovelySkin Customer

Verified Purchase

January 23, 2021

Youthful hands

I have been using Meg 21 morning and Evening for about three weeks now. I have very dry hands which cause them to look older than they should. I love the feel of this lotion. Instantly my hands look smoother and younger. It doesn't really have a smell and doesn't leave an oily feel. I plan to purchase again!!

Default profile picture.

LovelySkin Customer

Verified Purchase

November 18, 2020

Ok

Pro: I have noticed a reduction in my developing age spots. My hands do appear more even in appearance. However, I do not find this lotion to be particularly moisturizing. Given the small size and large cost, not sure it’s worth it and probably will look for a different product.

Profile picture of Tramany.

Tramany

Verified Purchase

July 28, 2020

WOW!

This hand lotion is amazing! My hands have been so dry especially now with washing my hands extra times due to the pandemic. I have tried so many other lotions and was never satisfied but this lotion is a WINNER!

Profile picture of MomofIrishtwins.

MomofIrishtwins

Verified Purchase

July 16, 2020

It Works

I’ve been using this product for a little while and it really does work. I was initially sent a sample and loved it so much that I decided to buy a full sized bottle. The backs of my hands, which were starting to look like crepe paper, are now smooth and hydrated. It’s non greasy and penetrates into my skin rather quickly. I wash my hands a lot and apply this throughout the day. I’m so thankful that my hands are looking much better.

Profile picture of Melissao.

Melissao

Verified Purchase

June 24, 2020

Beautiful results

If I had to say one thing that really shows a person's age- it would be their hands. I think they are often neglected. I received a sample of this and I ordered within a week of trying it. It smooths and plumps effortlessly. It is not heavy or sticky

Profile picture of Lada.

Lada

Verified Purchase

June 19, 2020

BEST HAND CREAM I HAVE EVER USED!!!

MEG 21 Top of the Hands HAND CREAM IS BY FAR THE BEST HAND CREAM I HAVE EVER USED! I will never again go searching for something that works because I found it! I am thrilled with the results and so quickly. HIGHLY RECOMMEND!

Default profile picture.

LovelySkin Customer

Verified Purchase

June 03, 2020

Better Than Not Using It

My hands are aging fast with all of the hand washing and gardening I'm doing this year. . . I liked how a sample of this made my hands feel. I notice the most improvement in appearance right after using it. Definitely makes them look younger, more luminous. Not sure it really has long term results, but I'm really putting my hands through a lot, so I don't know if I can really expect anything topical to turn back time. I'm 44.




Loading
Return to the top
877-754-6222
Need Help?
Email Us
Customer Care Hours
Mon - Fri 9 - 5 p.m. CT
Sat (chat only) 9 - 3 p.m. CT
Sun / Holidays Closed
Call or Text:402-697-1100