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Neocutis Bio Cream Overnight Smoothing Cream

(formerly known as Neocutis Bio-Cream (with PSP) - 50mL)
1.69 fl oz Face Cream
This product is no longer available

We recommend the following product instead:

Highlights

  • Best suited for dry skin types
  • Stimulates collagen with growth factors
  • Diminishes signs of aging with peptides

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Product Overview

Neocutis Bio Cream Overnight Smoothing Cream face treatment improves skin’s tone and texture.

Neocutis Bio Cream Overnight Smoothing Cream face treatment is a nighttime anti-aging treatment that nourishes skin and restores a more youthful glow. This anti-aging cream works to diminish fine lines, soften a rough texture, improve skin firmness and create a more even skin tone. PSP, the key ingredient in Bio-Cream, is a proprietary blend of growth factors, cytokines and interleukins. You’ll see visibly firmer, smoother and softer skin with continued use of this anti-wrinkle cream.

Key Benefits:

  • PSP smooths the appearance of fine lines and wrinkles
  • Antioxidants defend the complexion against free radicals
  • Clinically proven to reduce the appearance of wrinkles in just eight weeks

Use Neocutis Bio Cream Overnight Smoothing Cream to minimize the appearance of fine lines and wrinkles. 

All Neocutis products are gluten-free. While Neocutis Bio Cream Overnight Smoothing Cream and Neocutis Bio-Cream Riche (with PSP) do contain wheat germ oil, a wheat-derived ingredient, this ingredient was shown to be gluten-free by the supplier. Patch testing is always recommended with gluten-free products. Apply a small amount of the product to clean, dry skin and wait several hours. If inflammation, itching or irritation occurs, discontinue use immediately.

This product is packaged with an airless pump dispenser, which uses a vacuum system to dispense the product. Please see this product's directions for further information on airless pumps.

Neocutis product packaging will now feature a wafer seal instead of cellophane wrapping. Please note: sunscreens are the only Neocutis products that will contain printed expiration dates. If you have any questions or concerns regarding a Neocutis product you received from LovelySkin, please contact our Customer Care team.

Highlights

  • Gentle enough for sensitive skin
  • Diminishes fine lines and wrinkles
  • Improves skin tone and texture

Ingredients

Directions

Shipping & Returns

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Return Policy: This product is non-returnable

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Special Shipping Requirements: ORM-D Class
ORM-D classified products such as aerosol sprays, nail polish, perfume and products with high alcohol content may only be shipped using a ground method within the Continental US.

Availability: This product is no longer available.

Product Specifications

About the Brand

Customer Reviews (270)

Read all reviews
Profile picture of Scoobydoo.

Scoobydoo

Verified Purchase

September 10, 2024

Luxurious Night Cream with Amazing Results!

The Neocutis Bio Cream Overnight Smoothing Cream has become a staple in my nightly skincare routine. This cream feels rich and luxurious, yet absorbs quickly without leaving any greasy residue. After using it for a few weeks, I’ve noticed a visible improvement in the texture of my skin. It looks smoother, more hydrated, and even my fine lines appear less noticeable. I wake up with a refreshed, plump complexion every morning. It’s gentle enough for my sensitive skin, and I love how it supports my skin’s natural recovery overnight. Highly recommend if you’re looking for an effective night cream!

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LovelySkin Customer

Verified Purchase

March 09, 2024

Didnt like

Unfortunately I really wanted to like this but it did nothing for me. Didn't even hydrate or moisturize. Never bought again. Also didnt care for the serum.

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LovelySkin Customer

Verified Purchase

September 16, 2022

Great nightly moisturizer

I use this moisturizer nightly after my glycolic acid or retinoid. It is extremely moisturizing. A bit heavy, perhaps, but my skin is on the drier side, so I enjoy it. Those with less dry skin may prefer something less heavy. It has a bit of a play-dough type smell to it, in my opinion, but it seems to dissipate as worn. My skin is always refreshed and glowy (without being oily) in the morning. My skin is sensitive and acne-prone, and this does not irritate it in any way.

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LovelySkin Customer

Verified Purchase

July 12, 2022

Smooth on the skin

I love neocutis products, been using it for a while. Makes my skin smooth. Not oily but puts a little blt of shine

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LovelySkin Customer

Verified Purchase

April 15, 2022

Good for layering

I typically use serums, cream, and some oil after cleansing at night and this cream has been robust in that a little goes a long way. It’s also nice that it absorbs into my skin and I don’t wake up with a greasy face. Also back sleeper here so the cream isn’t going on pillows. It’s a keeper and I will purchase again.

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LovelySkin Customer

Verified Purchase

March 16, 2022

Staff Favorite

I bought this product because it was a staff favorite and liked it’s description. When I started using it, I only applied it to my neck and saw a difference in about a week. The crepiness is gone and the smoothing effect is not to be believed. I find myself touching my neck throughout the day just to feel how soft it is.

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LovelySkin Customer

Verified Purchase

March 15, 2022

Excellent Moisturizer

This moisturizer has worked great so far. I haven't noticed any changes in fine lines yet but it does make my face feel smoother.

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LovelySkin Customer

Verified Purchase

March 08, 2022

Smoothing Cream

The cream works well. It is gentle on my skin and non greasy. So far so good!

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LovelySkin Customer

Verified Purchase

March 01, 2022

Made me break out

I used Neocutis Bioserum for years but it became so expensive I had to stop using it. When a different cream was out of stock I ordered this, even though it was more expensive. I thought for sure I would love it, but it made my face break out like crazy.

Profile picture of LAZ.

LAZ

Verified Purchase

February 26, 2022

Favorable results

I have only been using this for a few weeks but have seen favorable results already. I mainly purchased this cream to use on my upper lip area where I recently had to have stitches. The scar is less noticeable since using this cream.

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LovelySkin Customer

Verified Purchase

February 16, 2022

Very good product

The texture of this cream is perfect for me. I've been using it for years and my facial skin looks pretty good for my age (63)

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LovelySkin Customer

Verified Purchase

February 14, 2022

Great night cream

This was first prescribed by a doctor. It absorbs well and improves skin quality.

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PrettySandy

Verified Purchase

January 24, 2022

Beautiful skin

This product goes on so smoothly and feels so good on my skin. I’m always being complimented on how good my skin looks!

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mudpie70

Verified Purchase

January 08, 2022

One of my staples

This has been my best find for a moisturizer. I use it at night however in the dry winter months I will also use it as my daily as well. Previously I used high end department store moisturizers. This is as good as they are if not better. And less expensive. My only drawback is not knowing when the container is getting close to being empty.

Profile picture of CYNTHIAJHOLLAND.

CYNTHIAJHOLLAND

Verified Purchase

December 31, 2021

Bio Cream

I love this moisturizer. I have very oily skin and this is non greasy and glides on for day or night moisturizer.

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LovelySkin Customer

Verified Purchase

December 28, 2021

Neocutis

I love neocutis products, I use this nightly and love the results. I will be using it as long as they continue to make the product.

Profile picture of Luckygrl.

Luckygrl

Verified Purchase

December 27, 2021

More love for neocutis

This is a great night cream. I need moisture but also something extra since it am in my 50s. My skin looks the best it ever has.

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LovelySkin Customer

Verified Purchase

December 23, 2021

Love this

I really see a difference in texture when I use this! It’s so expensive that I tend to go a long time before buying more every time I run out, so I tend to forget how great it is!!! But I love it :)

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LovelySkin Customer

Verified Purchase

December 04, 2021

Using for years

My dermatologist started me on this and it's great for my very dry sensitive skin. A little goes a long way so a bottles lasts for several months.

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LovelySkin Customer

Verified Purchase

November 29, 2021

Great night cream!

Makes your skin soft and smooth! Rich but not greasy. Takes away fine wrinkles. Improves complexion.




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