Hello! Thank you for your inquiry. • P-TIOX is recommended for twice daily application. For new users, we recommend beginning with 3-4 drops per usage, then increasing to 5-6 drops as tolerated. In the morning, apply after an antioxidant serum such as the SkinCeuticals C E Ferulic Antioxidant Serum and before moisturizer and sunscreen. In the evening, apply after Resveratrol BE and before retinol (unless RX). If using multiple corrective serums, it is recommended to layer from thinnest to thickest.

Hell. Thank you for your inquiry. The P-TIOX should be applied before retinol/retinoid (unless RX) in your evening regimen.

Hello! Thank you for your inquiry! The nine types of expression lines that the serum addresses are Nasolabial folds, Forehead wrinkles, Glabellar wrinkles, Crow’s Feet, Cheek folds, Marionette wrinkles, Dynamic under eye-wrinkles, Inter-ocular lines and the Global fine lines.

Hello. Thank you for your inquiry. SkinCeuticals P-Tiox and Cell Cycle Serum can indeed be used together to complement each other's benefits. Complementary Actions: P-Tiox addresses the appearance of wrinkles, while Cell Cycle Serum improves the overall skin texture. Together, they can create a smoother, more youthful complexion. Enhanced Effectiveness: Cell Cycle Serum helps to exfoliate the skin, allowing better penetration of P-Tiox's active ingredients. This can potentially enhance the wrinkle-reducing effects of P-Tiox. How to Use Them 1. Cleanse: Start with a gentle cleanser to prepare your skin. 2. Cell Cycle Serum: Apply a few drops of Cell Cycle Serum to your face and neck. This is generally recommended as the first step in your skincare routine. 3. P-Tiox: Once the Cell Cycle Serum has absorbed, apply a few drops of P-Tiox to the same areas. 4. Moisturizer: Follow with your preferred moisturizer. 5. Sunscreen: If using in the morning, apply a broad-spectrum sunscreen with SPF 30 or higher. Consistency is key when using skincare products. It might take several weeks to see significant results.

Hello. Thank you for your inquiry. •Yes, P-TIOX can be applied around the eye area (excluding the eyelid), and is proven to visibly reduce crow’s feet, dynamic under-eye lines, and inter-ocular lines. As always, avoid direct contact with the eyes.

Thank you for your inquiry. We would recommend adding this product into your routine in the following orders: AM TNS Advanced+ Serum Vitamin C P-TIOX Moisturizer SPF PM TNS Advanced+ Serum P-TIOX Retinol/Tretinoin Moisturizer We hope this information helps! If there is anything else we may assist with, please let us know. Thank you!

Hello. Thank you for your inquiry. The SkinCeuticals P-TIOX Wrinkle Modulating Peptide Serum is a water based product. You can use this product with any micro current devices.

Hello. Thank you for your inquiry. After using the vitamin C serum, If using multiple corrective serums, it is recommended to layer from thinnest to thickest.