SkinCeuticals P-TIOX Wrinkle Modulating Peptide Serum | LovelySkin
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SkinCeuticals P-TIOX Wrinkle Modulating Peptide Serum

SkinCeuticals P-TIOX Wrinkle Modulating Peptide Serum

1.0 fl oz
$148.00

Special Offer: Free $15 SkinCeuticals Discoloration Defense Deluxe Sample!

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Highlights
  • Smooths 9 types of expression lines
  • Complements neurotoxin injections
$148.00
$148.00
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Product Overview

SkinCeuticals P-TIOX Wrinkle Modulating Peptide Serum helps reduce nine types of contraction lines and promotes glass skin radiance.

Inspired by the effects of neurotoxin injections, this serum is formulated with an Advanced Peptide Complex and a Glass Skin Complex to smooth nine types of contraction and expression lines to rejuvenate skin for a renewed glow. Neurotoxin injections are a popular in-office treatment used to treat expression wrinkles caused by muscle contractions. 

When paired together, P-TIOX and neurotoxin injections work synergistically to help reduce the appearance of wrinkles, delivering fast, long-lasting results. Versatile and innovative, this serum is also effective on its own to smooth skin, refine pores and reveal glass skin radiance in one week of use. 

Clinical Results:

  • Improves skin smoothness, refines the look of pores and reveals glass skin radiance in one week
  • Visibly reduces fine lines in one week
  • Visibly reduces nine types of contraction lines, even those hard to treat with neurotoxin injections after 12 weeks
  • Visibly reduces global fine lines by 20.6% in 12 weeks

Key Features:

  • Advanced Peptide Complex, comprised of 2% hexapeptide and 2% dipeptide, works together in synergy to fight against contraction lines
  • 5% PHA, 5% niacinamide, and 1% laminaria extract maximize hydration while gently exfoliating to visibly improve skin texture and radiance
  • Tested on all skin tones and types
  • Hydrates skin up to 24 hours after application

Highlights

  • Smooths 9 types of expression lines
  • Complements neurotoxin injections
  • Reveals glass skin radiance

Ingredients

Featured Ingredients

Niacinamide

A water-soluble form of vitamin B3 that reduces the appearance of wrinkles.

Acetyl Hexapeptide-8

A synthetic peptide that relaxes muscle contractions to reduce the appearance of wrinkles.

Dipeptide Diaminobutyroyl Benzylamide Diacetate

A synthetic peptide that helps prevent the formation of fine lines and wrinkles.

Gluconolactone

A type of polyhydroxy acid that exfoliates but with less irritation than AHAs.

Laminaria Digitata (Algae) Extract

A marine plant extract that can improve skin hydration and thicken formulas.

Directions

Once or twice daily, apply 4-6 drops to the palm of the hand and dab onto the forehead, cheeks, and chin. Blend the product into the skin.

If using in the morning, apply after a SkinCeuticals antioxidant and before a SkinCeuticals moisturizer and sunscreen. If using in the evening, apply before a corrective cream or retinol.

If layering corrective serums, it is recommended to apply products from thinnest to thickest.

Shipping & Returns

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Return Policy: This product is non-returnable

Return Policy: View Our Return Policy

Special Shipping Requirements: ORM-D Class
ORM-D classified products such as aerosol sprays, nail polish, perfume and products with high alcohol content may only be shipped using a ground method within the Continental US.

Availability: In stock & ready to ship! . Ships within the U.S. only.

Questions & Answers (8)

Submit your question about this product to our talented team of Customer Care Representatives, and we'll get back to you as soon as possible!


Product Specifications

Item Id S43844
Item Id
Size 1.0 fl oz
Benefits
  • Smooths 9 types of expression lines
  • Complements neurotoxin injections
  • Reveals glass skin radiance
Skin Type
  • Combination
  • Dry
  • Mature
  • Normal to Oily
  • Normal
  • Normal to Dry
  • Oily
  • Sensitive
Product Type
  • Face Serums
  • Face Treatments
Key Ingredient
  • Niacinamide
  • Peptides
  • Salicylic Acid
  • Glycerin
  • Phytic Acid
  • Argireline
Product Form
  • Serum
Application Area
  • Face
  • Neck/Decolette
Concern
  • Crows Feet
  • Dry/Dehydrated Skin
  • Large Pores
  • Wrinkles
  • Dullness
  • Uneven Skin Tone
  • Barrier Repair
  • Sun Damage
Features
  • Dermatologist Tested
  • Hydrating
  • Staff Favorite

About the Brand

Customer Reviews (185)

Overall Rating

4.4
Based on 185 reviews

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185 Reviews

Profile picture of Glo.

Glo

Verified Purchase

May 01, 2025

P-TIOX Peptide serum

Excellent product. Highly recommend

0 people found this helpful

Profile picture of FancySusie.

FancySusie

Verified Purchase

April 29, 2025

Won’t do without it

I have added P-TIOX to my daily regimen. I am 73 yo and have used SkinCeutical products for about 30 years. I keep up,with all their new products and have never been disappointed. My skin looks so much better than most women my age. Expensive but worth it.

2 people found this helpful

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LovelySkin Customer

Verified Purchase

April 25, 2025

Glass Skin ALL Day

I’m so in love with this product. Not only does it instantly provide that glass skin look and radiance, but it also helps to clear up my breakouts and remove dark spots. Been using since the fall of last year and couldn’t be happier. Get so many compliments on my skin. A must try!

2 people found this helpful

Profile picture of LoriJ.

LoriJ

Verified Purchase

April 22, 2025

SkinCeuticals -P-TIOX

This is my new favorite, can’t live without,product. After getting a professional facial, I asked my technician what she had used below my eyes. My wrinkles seemed less noticeable. She had used the P-Tiox, which convinced me to buy some to take home. I’ve been using it once per day in the mornings before makeup. I use a few modest drops all over my face and neck, gently rubbing in a circular motion. It glides on smoothly and melts into my skin. Afterwards I top with my sunscreen/makeup. What I notice, besides a smoother appearing under eye area, is an extra glow to my skin, without using any type of blush. After using this product, my skin just looks nicer, and feels good, too.

3 people found this helpful

Profile picture of Debbye.

Debbye

Verified Purchase

April 21, 2025

Great product

I have reordered this product. I see a definite difference in my skin. I am 76 years old and moisture is very important. This product really hydrates my skins and reduces my wrinkles. Love it.

3 people found this helpful

Profile picture of Austin.

Austin

Verified Purchase

April 20, 2025

Not for me !

I am a skinceuticals fan- tried this sample and thought it works - so ordered a full bottle - after about two weeks of using it once every other day I started getting a rash - did not think it was this product behind it as I have the cleanser sunscreen, triple lipid, CE ferulic all from this brand for more than two years - needed prescription meds to clear my skin - after waiting two weeks I tried again - I got the same rash !! This time I know what caused it - not touching that bottle again !! I used it sparingly so the bottle is about 80% full :(

7 people found this helpful

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LovelySkin Customer

Verified Purchase

April 16, 2025

Fantastic glassy glow with Skinceuticals PTiox

An excellent serum to boost skins hydration, clarity, and glow that is noticeable with great results I love. The serum is moisturizing and luxuriously sinks into my skin enhancing it with sheen. PTiox is one of my favorite skincare produces to illuminate my skin with glassy glowy sheen.

4 people found this helpful

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LovelySkin Customer

Verified Purchase

April 15, 2025

This works

I am surprised at how well this works. I get Botox and this helps keep me smoother a little longer.

1 person found this helpful

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LovelySkin Customer

Verified Purchase

April 11, 2025

The best new product I’ve tried in years

This is by far the best new product I’ve tried in years. It does several things: it plumps my skin, it seems to be helping my pores look better, and it feels great on my skin. It is hydrating, but not at all too much so. It is expensive, but worth every penny, and it lasts very well. I use it after my vitamin C product and before sunscreen. My dermatologist recommended it and I’m so glad she did!

2 people found this helpful

Profile picture of KellyinOrlando.

KellyinOrlando

Verified Purchase

April 06, 2025

It’s just ok

I’ve been holding on writing this review until I had a month under my belt. The product is just ok. I really haven’t noticed a difference to my skin. The product is gentle and good with my sensitive skin. And I like that it’s not fragranced. Will not repurchase.

4 people found this helpful

Profile picture of KLBM.

KLBM

Verified Purchase

April 05, 2025

Love!!

This product pairs great with your regular Botox injections. It really helps keep your wrinkled areas smooth in between visits. The product is very moisturizing as well.

1 person found this helpful

Profile picture of Keh.

Keh

Verified Purchase

April 04, 2025

SkinCeuticals P-TIOX

This brand consistently creates top quality, innovative products that provide real results. I wanted to try this serum ever since it was first released due to the ingredients and claimed benefits. It is expensive, but due to the consistently, a little goes a long way. While it's early, I do notice some decrease in forehead lines. I have to compliment the customer service staff, as they were very pleasant and helpful during the almost 2 weeks it took to receive the product.

0 people found this helpful

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LovelySkin Customer

Verified Purchase

April 03, 2025

Seeing subtle differences

I started using this product about ten days ago and I have indeed noticed improvement. I'll report back at the end of 12 weeks, but I am optimistic that I will be even happier. I also use other products on my skin, including C E Ferulic, so this product is an addition to my skincare regime. For reference, I am almost 71 and I often get compliments on my skin and hear that I do not look my age. While I've used Botox in the past, it's been 11 months since my last injections, which I typically schedule 2-3 times a year.

2 people found this helpful

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LovelySkin Customer

Verified Purchase

March 31, 2025

Made My Skin Breakout

This may be a wonderful product but after two weeks of use my skin had so many whiteheads I discontinued using it. My skin immediately cleared up after I stopped using it.

4 people found this helpful

Profile picture of ShBennett.

ShBennett

Verified Purchase

March 30, 2025

Slight improvement on forehead lines.

I noticed a slight improvement after completing the first bottle on my forehead lines, I did purchase a 2nd bottle to give it a fair chance. I use it only once a day, so I thought 2 bottles was a fair chance. Will have to update when I'm finished with the 2nd bottle. It absorbs quickly, and I put it on after my vitamin c serum.

2 people found this helpful

Profile picture of TMoss.

TMoss

Verified Purchase

March 29, 2025

Didn't work for me

I was so excited to try this product based on the description and customer reviews. I have now completed my second bottle, but see minimal difference in fine lines and wrinkles. Perhaps I didn't experience the same results because I do not get neurotoxin injections, however, annually I do get CO2 fractional laser resurfacing.

4 people found this helpful

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LovelySkin Customer

Verified Purchase

March 27, 2025

Like it But Still Waiting….

I believe this is helping my deeper wrinkles. I’m on my second bottle and see temporarily results when I use the serum. I suggest giving it a try but realize one bottle won’t eliminate the need for Botox if you’re a user.

1 person found this helpful

Profile picture of KBellino.

KBellino

Verified Purchase

March 25, 2025

Glass skin

Absolutely loving it…it’s definitely a must add to your skin care daily!!

0 people found this helpful

Profile picture of sharmon.

sharmon

Verified Purchase

March 22, 2025

Real results

I've used one bottle of this new formula. I noticed a difference in the nasolabial folds and wrinkles that were forming at my jawline. I haven't noticed much improvement in the deeper lines in my forehead. I use a little more than is directed and it still lasts for quite a while. I would recommend this product.

1 person found this helpful

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LovelySkin Customer

Verified Purchase

March 22, 2025

Really works

Impressed with results and non greasy

0 people found this helpful

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