When applied twice a day as recommended, the serum should last roughly four to six weeks.

TNS® stands for Tissue Nutrient Solution, which is SkinMedica's patented growth factor blend.

Many of our customers have found the SkinMedica TNS Advanced+ Serum to be an important part of their regimen. Want to hear it in their words? You can check out customer reviews here.

Thank you for your question. This product does not contain Vitamin C.

If SkinMedica TNS® Advanced+ Serum is causing your skin to peel, it could be due to several factors, such as overuse, skin sensitivity, or a reaction to the active ingredients in the serum. Here are a few strategies to help prevent peeling and improve the overall experience with the product: 1. Start Slowly If you’re new to the product, it's important to gradually introduce it into your routine. Start by using it 2–3 times a week, and then slowly increase the frequency as your skin builds tolerance. This helps minimize irritation and peeling. 2. Use a Moisturizer Pair the serum with a good moisturizer to help lock in hydration and maintain your skin's moisture barrier. Dry skin can exacerbate peeling, so keeping your skin moisturized is key. Apply the moisturizer after the serum has fully absorbed. 3. Avoid Layering with Other Exfoliating Products If you're using other products that contain exfoliating ingredients (like retinol, glycolic acid, or vitamin C), these could be causing your skin to peel when combined with the TNS Advanced+ Serum. Limit the use of other exfoliants on the days you're using this serum. 4. Use the Right Amount Using too much of the serum can increase the likelihood of irritation and peeling. Apply a thin layer to your skin and allow it to absorb before applying any other products. Overloading your skin can lead to unwanted side effects. 5. Apply to Dry Skin Make sure your skin is completely dry before applying the serum. If your skin is too damp, it can increase the chances of irritation and peeling because the serum may be absorbed too quickly or unevenly. 6. Protect with Sunscreen Exfoliation and the use of active ingredients can make your skin more sensitive to the sun. Ensure you're applying a broad-spectrum sunscreen during the day to protect your skin and prevent further irritation or peeling. 7. Check for Sensitivity If peeling persists or becomes severe, you might be sensitive to one of the ingredients in the serum. In such cases, you might want to reduce the frequency of use or discontinue the product entirely and consult with a dermatologist to determine the best course of action. If the peeling continues despite trying these steps, or if it becomes painful or excessive, it’s important to consult a dermatologist to assess your skin’s reaction to the serum and ensure it’s appropriate for your skin type.

Hello. Thank you for your inquiry. The SkinMedica TNS® Advanced+ Serum can be used along with Vitamin C (like Skinceuticals) in the morning without issues. These products can complement each other since they work in different ways to improve skin tone, texture, and overall appearance. For the night, you might want to alternate between TNS Advanced+ Serum and your retinol/benzoyl peroxide treatment. Using them on the same night could lead to irritation, especially since retinol and benzoyl peroxide are both strong actives. For example, you could use TNS Advanced+ Serum on one night and retinol/benzoyl peroxide treatment on another. Always patch test first if you're concerned about how your skin may react to combining these actives.